Welcome to the homepage of LBI-HTA !
The LBI-HTA is an acadmic non-profit institute and belongs to the Ludwig Boltzmann Society. At our website we wish to present our research and give support for health care decision-making. Here all of our reports are available for free. For further information please contact the LBI-HTA team.
Hadron therapy in children: evidence synthesis for 15 paediatric tumours. Report based on Belgian (KCE) HTA report
A Belgian KCE-Assessment analysed – as an update of the 2007 report – the evidence for hadron therapy (proton and carbon ions) in 15 paediatric indications. Since 2015 the Austrian MedAustron started operating and the first patients are treated, the LBI -HTA has been involved in the Belgian report as external expert. Now the LBI -HTA wrote – due to the regional relevance – a German summary of the Belgian report.
In the assessment 21 clinical studies (non-randomized, non-controlled and mostly retrospective) were found. All studies showed serious methodological flaws. The conclusion therefore is that to date clinical data on PBT in all paediatric cancers under study are lacking as well as critical information on long-term effectiveness and harms.
Prospective comparative clinical trials in the field are urgently needed.
Publication: Decision Support Document Nr. 88: http://eprints.hta.lbg.ac.at/1049
Contact: Claudia Wild
Vasoprotectives: Efficacy and safety of capillary stabilising agents for venous insufficiency or haemorrhoidal diseases
The systematic review assessed the efficacy and safety of a treatment of chronic venous insufficiency (CVI) and haemorrhoidal diseases (HD) with capillary stabilising agents that are listed in the Austrian Code of Reimbursement.
A total of 56 studies were included for a data synthesis.
The majority of studies have shown that the symptoms and signs of CVI and HD can be reduced slightly with the agents (mostly when compared to placebo). Only minor side effects occurred.
However, the strength of the evidence of nearly all identified studies is low. Therefore, we cannot draw a final conclusion on the efficacy of capillary stabilising agents for the treatment of CVI and HD.
Publication: LBI-HTA Project report No. 79: http://eprints.hta.lbg.ac.at/1047
Contact: Stefan Fischer
In nearly all Western countries, HTA-reports on Positron Emission Tomography/PET imaging have been written in the last two decades. 155 only in the last 10 years (!) Hardly any other medical technology has undergone so many evaluations. This large abundance is ultimately an expression of an unfading uncertainty about the value of PET imaging in patient care. The (Austrian) HTA report has the intention of supplying decision support for evidence- and needs-based PET device planning. Results from 35 HTAs and recommendations from 7 medical societies have been taken into consideration in the HTA report.
Publication: LBI-HTA Project report No. 77: http://eprints.hta.lbg.ac.at/1045
Contact: Claudia Wild
The event is organized in a cooperation between LBI-HTA/ Ludwig Boltzmann Institute for Health Technology Assessment and TI-AC/ Transparency International – Austrian Chapter.
Tuesday, March 3, 2015, 4:00 p.m. to 6:00 p.m.
Library of the Medical Society
We are pleased to introduce our new HSO report.
This report provides an overview of possible applications and the current evidence on the effectiveness of acupuncture. Recommendations of the WHO and professional associations as well as the results of an overview of Cochrane Reviews are compared with 25 approved indications from the Austrian Health Council (Oberster Sanitätsrat, OSR), an advisory committee for the Ministry of Health and enables to identify indications for which (in)effectiveness is proven.
Publication: LBI-HTA Project report No. 78: http://eprints.hta.lbg.ac.at/1042
Contact: Brigitte Piso
Project / High tech medicine
Project leaders: Claudia Wild
Project co-operation: LBI-HTA staff for individual reviews
Duration: November 2014 – April 2015